This fixture pitting the two regional giants will see Rwandan captain Haruna Niyonzima who plies his trade at Yanga face his former employers in familiar territory.
Niyonzima, an attacking midfielder whose creative prowess has earned him legendary status in Rwanda, is expected to play a defining role in this tie.
Yanga qualified for the Champions League first round after eliminating Cercle de Joachim of Mauritius on a 3-0 aggregate in the preliminary round.
Yanga won 1-0 in the away leg with the goal scored by Donald Ngoma before Amissi Tambwe and Thabani Kamusoko scored each a goal in the return leg in Dar es Salaam.The three international strikers are again expected to be in the Yanga squad.
APR eliminated Mbabane Swallows as central defender Abdul Rwatubyaye hit a hat trick and midfielder Patrick Sibomana added one goal as the Rwandan champions overturned a 1-0 deficit from the first leg to win 4-1, and progressed to the next phase 4-2 on goals aggregate.
The Rwanda international youngster opened the scoring in the eighth minute after a well taken free kick from Jean-Claude Iranzi. The 19-year old added a second seven minutes later, again from an Iranzi corner and he completed a historic treble in the 75th minute, with Iranzi once again the provider.
Amavubi winger, Iranzi, was at it again, this time setting up Sibomana for the fourth goal in the 90th minute.
Mbabane Swallows consolation goal was scored in the 26th minute by Sanele Mkhweli after his shot was deflected by Emery Bayisenge.
Yanga coach Hans van der Pluijm says that his players were in good morale of winning that away game.
“We have fully prepared to face them. APR is a good team,” Pluijm said.
APR coach Emmanuel Rubona said that Yanga was a strong team composed of experienced players.
The return leg will be played after two weeks at the National Stadium in Dar es Salaam with the winner of this tie facing Egyptian giants Al Ahly in the second round.